To determine the mechanisms underlying familial lethal arrhythmias with a focus on diagnosis and treatment of genetic and electrophysiological abnormalities of the heart.
We welcome graduate students and Post-Doctorate researchers interested in cardiac electrophysiology and the genetic basis to arrhythmias. Please look through our Research page to see our recent projects. If you are interested in joining us, please contact Professor Makita at firstname.lastname@example.org.
A Japanese Long QT registry paper was accepted in JAMA Cardiolol
A collaborative paper about laminopathy with NCVC was accepted for publication in Cir J
A collaborative work with Dr. Naokano in Hiroshima University was accepted in Circulation: Genomic and Precision Medicine.
An international collaboration paper about SCN1B mutations related to inherited lethal arrhythmia was accepted for publication in Heart Rhythm Journal.
We had a Farewell and Welcome party for Mr.Hiroki Kimoto, Ms.Yumi Matsuo and Yoko Komori.
A collaborative research paper was accepted by Am J Physiol Heart Circ Physiol.
A collaboration paper with Professor Takano in Department of Physiology, Kurume Medica Univeisity was accepted for publication in J Physiol.
Dr. Ishikawa was awarded the research grant from the Miyata Cardiac Research Promotion Foundation.
Dr. Ishikawa was awarded the 2017 JCS basic cardiovascular research grant.
Dr. Ishikawa was awarded the 2017 Kenzo Suzuki Memorial Foundation research grant.
Dr. Taisuke Ishikawa was promoter to Lecturer as of Oct 10 2017
A collaborative research paper was accepted by Circulation Cardiovascular Genetics
A collaborative research paper on postmortem genetic analysis of sudden unexpected death in infancy with the Department of Forensic and Pathology and Science was accepted for publication in J. Hum. Genet.
A letter to the editor on feline LVNC has been accepted for publication in JVIM.
A research paper on progressive cardiac conduction defect in collaboration with an INSERM group in Nantes France has been accepted for publication in JACC
A collaborative research paper about the genome editing of iPS-cardiomyocytes derived form a patient with long QT syndrome carrying a CALM2 mutation has been accepted in Hum Mol Genet.
A research paper about a hot spot mutation for the short QT syndrome was accepted by JACC: Clinical Electrophysiology.
A Japanese multicenter registration study on Brugada syndrome was accepted by Circulation.
Dr. Ishikawa was awarded the Japan Heart Foundation Dr. Hiroshi Irisawa & Dr. Aya Irisawa Memorial Research Grant.
An iPS-based collaborative research paper about Andersen-Tawil syndrome was just published in Biochemistry and Biophysics Reports.
Dr. Ishikawa’s paper about familial sick sinus syndrome was just accepted by Heart Rhythm.
Dr Ishikawa wins the Fukuoka Marathon for two years in a row.
PhD student, Hiroki Kimoto won the first prize of Kyushu Research Award during the Annual Meeting of West Japanese Physiological Society.
A case report of aborted cardiac arrest with a novel CALM1 mutation was accepted in HeartRhythm Case Reports.
A research paper about an overlap syndrome of Brugada and long QT syndrome using human iPS-derived cardiomyocytes has just been accepted by Scientific Reports
AMED On-Site Grant Review was performed in Department of Medicine, Nagasaki University
A collaborative research paper with Niigata University was accepted by Journal of AHA
Institutional fees for genetic screening of long QT syndrome
Welcome new Medical Students to Molecular Physiology Department.
A collaborative paper with INSERM titled “Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I” was accepted to International Journal of Cardiology.
Dr. Tsuji receives the Senshin Medical Research Foundation grant.
Dr. Tsuji published a review titled “Electrical Storm Associated with Inherited Arrhythmia Syndromes: Cardiac Purkinje Fiber Arrhythmogenesis” in the Japanese Journal of Electrocardiology.
Dr. Ishikawa runs the Fukuoka Marathon.
Professor Makita was awarded the 2015 Kenzo Suzuki Memorial Foundation research grant.
Dr. Ishikawa published a review article entitled with “Inherited Bradyarrhythmia: A Diverse Genetic Background” in Journal of Arrhythmia.
A collaborative work titled “Molecular Mechanisms Underlying Urate-induced Enhancement of Kv1.5 Channel Expression in HL-1 Atrial Myocytes” with Dr. Maharani, has just been accepted by Circulation Journal.
A collaborative work titled “A collaborative work, “Fibrosis, Connexin43 and Conduction Abnormalities in the Brugada Syndrome,” with Dr. Koonlawee Nademanee, has just been accepted by Journal of American College of Cardiology.
A new AMED (Japan Agency for Medical Research and Development) Grant was accepted.
A collaborative work on the role of transcription factor in cardiac conduction disturbance with Dr. Akiko Koizumi of Tokyo Medical and Dental University, has just been accepted by European Heart Journal.
Dr. Taisuke Ishikawa received the research grant from Takeda Science Foundation.
A collaborative work, “Functional characterization of rare variants implicated in susceptibility to lone atrial fibrillation”, with Dr Kenshi Hayashi in Kanazawa University, has just been accepted by Circulation: Arrhythmia and Electrophysiology.
A collaborative work, “On June 10th, Dr. Mochizuki of the National Cerebral and Cardiovascular Center will be giving a graduate school seminar on “heart-vascular development research by imaging of zebrafish.
“An original research paper about Short QT Syndrome by Daniel Harrell titled “Genotype-Dependent Differences in Age of Manifestation and Arrhythmia Complications in Short QT Syndrome” has just been accepted by International Journal of Cardiology.
An original research paper by Dr. Taisuke Ishikawa titled “A Novel Mutation in the α-Myosin Heavy Chain Gene Is Associated with Sick Sinus Syndrome” has just been accepted by Circulation: Arrhythmia and Electrophysiology.
Dr. Taisuke Ishikawa wins Moderated Poster award at European Society of Cardiology congress.
An epidemiological study about cardiac conduction disturbance was published in International Journal of Cardiolology (First author: Dr. Kusumoto, Dept of Cardiovascular Medicine, Nagasaki University)
Professor Makita published new research paper on a novel CALM2 mutation associated with congenital Arrhythmia Susceptibility.
Dr. Tsuji published a review article on the Molecular mechanism of Heart Failure progression associated with ICD shocks in Journal of Arrhythmia.
An original research paper about sick sinus syndrome written by Dr. Keisuke Abe, previously our MD-PhD course student, has just been accepted by Circulation: Arrhythmia and Electrophysiology.
Dr. Taisuke Ishikawa won the first place in the Clinical Investigation Section of Circulation Journal Award For 2013.
Associate Professor Matsumoto receives Ryojun Teaching Award.
1,000 Genome: Our Collection of the Genome DNA from patients with lethal arrhythmias has reached 1,000 samples.
A Graduate School Seminar will be held on March 24. We will invite speakers, Dr. Jean-Jacques Schott (INSERM, France) and Professor Minoru Horie (Shiga Medical University)
Dr. Naomasa Makita collaborated in the publication of original articles in Europace.
Dr. Taisuke Ishikawa received the Fukuda Foundation for Medical Technology research grant.
Dr. Yukiomi Tsuji receives the Suzuken Memorial Foundation grant.
Three new original articles and one review published in Asia Pacific Heart Rhythm Society’s Journal of Arrhythmia.
Dr. Taisuke Ishikawa wins the Young Investigator Award at the 64th West Japan Symposium of the Physiology Society of Japan.
Dr. Taisuke Ishikawa receives the Best Paper Award from the Japanese Society of Electrocardiology.
Brugada GWAS paper published in Nature Genetics.